Continuing on the “shoulders of these giants” and reviewing and dissecting the expanding horizon of publications on B. In 1993, Drobniewski ( 40) published a major review in this journal, entitled Bacillus cereus and Other Related Species, which followed “Farrar's landmark review” published 30 years earlier ( 45). cereus infection while awaiting antimicrobial susceptibility results for the isolate include ciprofloxacin and vancomycin. Antimicrobials noted to be effective in the empirical management of a B. cereus produces a potent β-lactamase conferring marked resistance to β-lactam antibiotics. Primary cutaneous infections mimicking clostridial gas gangrene induced subsequent to trauma have also been well documented. Its role in nosocomial acquired bacteremia and wound infections in postsurgical patients has also been well defined, especially when intravascular devices such as catheters are inserted. Outside its notoriety in association with food poisoning and severe eye infections, this bacterium has been incriminated in a multitude of other clinical conditions such as anthrax-like progressive pneumonia, fulminant sepsis, and devastating central nervous system infections, particularly in immunosuppressed individuals, intravenous drug abusers, and neonates. cereus when isolated from a clinical specimen is overcoming its stigma as an insignificant contaminant. Among these secreted toxins are four hemolysins, three distinct phospholipases, an emesis-inducing toxin, and proteases. cereus, whether intestinal or nonintestinal, is intimately associated with the production of tissue-destructive exoenzymes. cereus is associated mainly with food poisoning, it is being increasingly reported to be a cause of serious and potentially fatal non-gastrointestinal-tract infections. Summary: Bacillus cereus is a Gram-positive aerobic or facultatively anaerobic, motile, spore-forming, rod-shaped bacterium that is widely distributed environmentally.
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